Showing posts with label article. Show all posts
Showing posts with label article. Show all posts

Wednesday, February 20, 2013

News Article: Why Women's Eggs Don't Last

A human oocyte.FLICKR, ED UTHMAN

It's late and I'm tired, but I've been meaning to post about this since last week. My BFF sent it to me the same day we got our twins u/s report and I wasn't ready to share our news with him yet. Will have to have a talk with him at sometime to explain "timing" and how it relates to "appropriateness", but fortunately our u/s went well. Anyhow - since I wasn't in anguish over my old-ass eggs that day, I was able to read the article as it was intended.

The article is a very interesting read regarding how egg quality declines as women age. Too tired to go into my analysis of it so I will just give you the link outright. :-)

http://www.the-scientist.com//?articles.view/articleNo/34375/title/Why-Women-s-Eggs-Don-t-Last/

This really doesn't help me that much because of my age, but I do think it has great potential for others 10+ years from now, with a hope of pharmaceutical help to all ages of women. That would be freaking fantastic. 

Tuesday, January 1, 2013

How to be Good Friends with an Infertile

Excellent read for those of you that are not infertile, but really want to know how to be awesome to those of us who are. Hell, who am I kidding? Excellent article for us infertiles to pass on to our fertile friends. At least the ones that haven't already violated every "do not" on the list already...

http://tertia.typepad.com/so_close/2004/05/how_to_be_good_.html


Thursday, October 25, 2012

Backscatter and IVF

Every since we've started IVF, I avoid the backscatter machines like the plaque. Even a tiny bit of radiation is too much risk in my head. My husband does as well, but for totally different reasons. Turns out I'm not the only one: The New York Times wrote X-Ray Scans at Airports Leave Lingering Worries back in August and it seems to back up my position. Nothing really definitive, but enough to make me continue my avoidance of the backscatter machines. If you are trying IVF (or pregnant) and flying, it may be worth the read.

Interestingly enough, I almost ran into a problem with this on our return flight from India in the Amsterdam airport. They have long had scan machines* in place and from my experience, it is EXTREMELY uncommon for people to opt-out. Caused a bit of commotion last time when I was trying to opt-out and the agents were trying to convince me it was safe. I kept repeating "my doctor specifically told me NOT to go through those." I hadn't really talked to any doctor about it, but it was all I could think of at the moment. The agents then tried to explain that the metal detectors were a higher risk than the backscatter machines (I have found out since then that this is not true in cases of pregnancy; I can't vouch for other medical issues.)

The female of the duo agents finally stated "they are even safe if you are pregnant" to which I gave a notable pause. "Even IF you are pregnant? Because my doctor said NOT TO." Apparently my long pause, semi-panic attitude, and adamant stance made HER pause. "Are you pregnant?" I had to think quick. The line from GhostBusters hopped in my brain "If someone asks if you are a God - YOU SAY YES!" And so I lied. "Yes, I'm 40 years old, high risk for miscarriage, and my doctor told me not to go through those."

At this, the female agent waved off the male agent, pulled me to the side, gave me a pat-down, and said congratulations. Did I feel bad for lying? Yes. No. Maybe. That congratulations was a bit stingy, but ok. I'll take it. Way better than me worrying about the alternative.

Woman are born with a finite set of eggs. We make no  more. We have to protect what we have. There are no long term studies on the effects of these machines and in many cases they aren't calibrated/tested regularly. If something went awry, you would probably never hear about it. When you get an x-ray, even if it is faaaaarrrrrrrrr from your ovaries (like an ankle x-ray I had a few years ago), they place a little protective pad over your abdomen to protect your ovaries. As far as I'm concerned, that pad is there for a reason, and I'm not lowering my chances one single bit.

* The Amsterdam airport is said to use a different technology than the normal backscatter machines we have in the US. They call it "Security Scan" and it uses millimetre waves that bounce
off the skin and do not enter the body. To my knowledge, long term studies have not been performed on them. 

Sunday, October 7, 2012

New Advances in Infertility

Each of these mouse pups was born from an egg scientists created using embryonic stem cells. 
On thursday, NPR had a fascinating story on a breakthrough discovery for infertility. Even more fascinating  they did it with induced pluripotent stem cells (as opposed to the controversial embryonic stem cells). If they can do it for women, then not only will it reduce/eliminate the biological clock worry, but also provide a solution for the dreaded "unexplained infertility" diagnosis that plagues so many women. This will be a game changer for future generations of infertile women. There are even great implications for men with sperm issues, as well  as the many hurdles faced by the LGBT community.

Alas, this will not apply to many of us currently in the throes of infertility. All is not lost. Many doctors are currently working on various cell technologies that apply to infertility. Autologous Endometrial Coculture is one example of a technology promising encouraging results. What does all that fancy wording mean? The short of is that they take cells from the lining of a woman's uterus and use them as a more natural environment for fertilized eggs than the previous methods. Studies have shown that in certain cases embryo development is improved, as are IVF success rates.

Dr. Patel's clinic in India is working with a similar concept: certain clients can qualify for the case study in which natural cells from the IVF patient are used to surround the egg pre-fertilization. They are seeing an increase in fertilized eggs and while it's too early to determine if this results in actual healthy babies born, I can say I was very impressed to learn that 3 out of 4 of my eggs were fertilized with this method. There is more to this method than I am [purposely] describing, but that is better left to the professionals or perhaps, when I can be less emotionally attached to the subject matter.

I have no idea if this will help the quality of my eggs/embryos in the long run, but it is still very exciting. My first cycle ended up with 2 eggs and only 1 of those fertilized. That 1 egg took over 24 hours to fertilize. On my second cycle (with the new protocol) I had 4 eggs extracted and out of those 3 fertilized. Like my first cycle, one of those was a late bloomer, but maybe it's the one implanted now and thus causing a lower hcg. Apparently my case is not an anomaly as the Akanksha Infertility Clinic is seeing really encouraging results with women that qualify for the case study. Even if it doesn't work for me, I will be really excited if this helps improve success rates for women in general.

Science is so cool. 

Sunday, September 16, 2012

Good article about surrogacy in India

Not familiar with this news source here in India, but the few articles I perused were done quite well. The article they have on surrogacy is here: http://gulfnews.com/life-style/general/india-s-rent-a-womb-industry-is-booming-1.1073056. Though I don't particularly care for the first picture they have in the slides, the article is a positive one none-the-less. Worth the read.

Note: the article is a bit confusing when it is referring to clinics . Even as a person who knows a ton about my clinic, I had some confusion when they flip between some details about clinics. For example, on page  1, the author writes "Parvati works for – Akanksha Infertility Clinic" and noting earlier that is is located in Ahmedabad. Then they flip to "Dr Kamini Patel, the director of Vani IVF Centre, in Ahmedabad". Even though these two clinic are in Gujarat and both have a Dr. Patel, they are two completely different clinics. The article flips back and forth between quotes from Parvati and quotes from Dr. Kamini, that it sounds like they are the same clinic. I actually wonder if they just misprinted which clinic Parvati was with. 

Also, while the Vani IVF Center they refer to frequently and write as having 48 surrogate babies born, I do want to note that Dr. Nayna Patel at the Akanksha Infertility Clinic has had over 500 surrogates born as of June of this year. I know this because I was here for the HUGE celebration, flanked with media from all over. I include this information because I can see that the most people would confuse the two clinics when reading the article

Tuesday, August 28, 2012

Special Lady Cocktails

When I first was swept up by the internet infertility tornado, I remember reading forum posts from other hopeful women. Falling on a theme (as I often do), I obsessed over the ridiculousness of women taking all kinds of crazy pills - usually without having a doctor recommend them. OMG! DO YOU JUST TAKE ANYTHING YOU FIND ON THE INTERNET??? Some posts swore by the helpfulness while others confessed that they worried it may have hurt. Once discovered, some doctors gave full-on lectures how it was not appropriate for the poster's situation, only to find out that someone else (usually another doctor) in their clinic had told them to take it. Truthfully, I was personally affronted that such naivety and desperateness could drive women to arbitrarily take anything in an attempt to conceive.


The picture above is from MY house. That's right, Ms. Holier-than-thou is ...well, the same as everyone else.

At first it started small. My first pill was THE PILL, and I was told I would have to take it by my Indian doctor to make sure I was synced properly for my IVF treatment. Fair enough. I called my OB/GYN and promptly got a prescription. Let me mention here that I do not like taking birth control pills (bcp) as not only does it make me gain weight and experience occasional nauseousness, but sometimes I experience additional glum side effects (depending on the brand). Fine - whatever - I set my alarm on my phone to give me a daily reminder; particularly because my history of remembering to take medicine on a daily basis is pretty dismal. Especially BCP. Our local IVF doctor also advised to add a pre-natal vitamin (another item bound to make me nauseous) and I immediately relented as I ran to our local Publix.

Baby aspirin and acupuncture were added to the regime - the latter being something I normally would have scoffed at a year earlier. Doctor semi-recommend it and so I shelled out the cash. My husband gave me the big-eye, but I'm guessing he recognized my fervent look and said nothing. 100 bucks a pop for 6 weeks = not cheap. What can I say except I wanted no regrets.

IVF treatment #1 was dismal. 2 eggs retrieved, only 1 fertilized. Even that 1 took a damn long time to fertilize.

Now I am prepping for treatment #2. In typical fashion, I have been obsessively researching similar cases. Not just blog posts, but academic papers and any type of current research I can lay my grubby little eyes on. A clinic in India recommended 25mg of DHEA for 3 months. I rush to pull up the scientific documentation and realized all of the research is really based on a tiny Tel Aviv study. The study showed a significant difference in live birth rates with women who were poor responders and took 75mg of DHEA for 40 days vs women who did not. A follow-up study had additional encouraging results. Screw the 25mgs -I only had about 40 days till cycle, I was going to go full boat - 75mgs it is! [I would like to make a note here that I was not able to take the full 75mg initially because of side effects. I had to build up and even now I have minor side effects.]

Next I read how melatonin could also help woman with poor ovarian reserve and immediately I was hunting down more articles and recommended amounts. 3mgs seemed to be the magical number, but that amount knocked me on my butt. Still 1-2mg was doable and thus it was added. Combining it with the DHEA means I sleep really well, but I'm groggy as all get-out when I wake up. Heaven help me if I don't get a full 8-9 hours. Oddly enough, my friend says she takes 10mg all the time and it barely helps her sleep. What can I say? I'm a lightweight.

Did I stop there? Heck no! I was on a search that day and after reading some articles (which I can not find at the moment) regarding myo-inositol, my amazon shopping cart increased. Among other things, myo-inositol was suppose to help women with cyst issues and a giant cyst almost caused a no-go last cycle. My OB/GYN found a cyst last year and I began to wonder if some of the pain issues I had felt over the last year were cyst related. GIVE ME MYO-INOSITOL NOW!!!

There were a few other things on the list, but these 3 new items had good scientific data to back them up and they applied to women with similar (if not exact) conditions. The other pills I noticed my fellow women-at-arms were taking were either less scientifically regarded or didn't apply to me. Besides, as I mentioned before, I'm a light weight and I wanted to see how I was going to handle this new concoction.

Which brings me to last week. I'm not quite sure HOW I ended up at the Rainbow (read: hippie) Grocery store - but all of a sudden I found myself at the cashier's stand with CoQ10, some fancy fish oil supplements, and yes even some Royal Jelly that was well hidden in a jar of honey. And some awesome low-sugar dried mango. And a yummy nut mix. And Activated Charcoal that I told myself would be good to have on hand if my dogs ever get into something they shouldn't. Somehow I think my subconscious was trying for an easy excuse to get some for me. You know. Just in case.


"Just a spoon full of sugar..." (or honey) 

Sunday, July 22, 2012

Open letter to The Hindu (newspaper)

Thanks to Douglas over at Just One Out of Seven Billion for bringing an article by The Hindu, to my attention.  Below is an open letter to the editor based on a similarly emailed letter.

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Regarding your article here: http://www.thehindu.com/news/national/article3640405.ece, I am surprised and saddened to see such a bias-based article written by The Hindu. There are several misrepresentations that I will list for your consideration.


1.) Thanks to the emergence of surrogate motherhood as a multimillion-dollar industry in the country, the clinic is doing a roaring business. What is the success formula? An unending supply of poor and illiterate women and the absence of laws have made the trade the fastest way to make money.

No source referenced here (a mainstay of good journalism) on how the author came to the conclusion that this specific clinic's success is based on [the uteri] of poor/illiterate women. No mention on how the clinic in question has put a lot into the community to educate the surrogates and their children. No mention of the trust fund set up to assist current and previous surrogates to further themselves and their family. A simple query into the community will show you that Dr. Patel is highly revered for all she has done to help the women in her care. Simple research into print editions of The Times of India (Ahmedabad edition) or Hindustan Times would have shown this as well. Had the author inquired into proof of how the surrogates have had their lives changed by this clinic, then Dr. Patel would have been able to provide this.


2.) Another inmate had four foetuses in her womb, two of which were aborted as the couple did not want so many children. There is no clarity on whether two foetuses were aborted for medical reasons. 

Using the emotional term "inmate" aside,  a woman carrying 4 foetuses to full term is in extreme danger, as are the foestuses. A rudimentary check with a few respectible obstetricians would have enlightened this fact. A woman's survival rate and the babies survival rate is seriously compromised and often considered not worth the risk. A doctor that WOULD allow this should draw much more concern as in cases where it is allowed, it would appear that the woman's health is not the priority.


3.) A commissioning couple can get a surrogate for half the price in India compared to the cost in the U.S. or the U.K., where surrogacy is not allowed or permitted only in special cases. European countries do not allow surrogacy at all. 

While I could lament on the economic differences between these countries and how comaparing them is extremely misleading, I will simply point out the cost of the average 1000 sqft flat in Vastrapura (located in the state of the clinic mentioned in this article) to allude my point: the [current] equivelent of 12-16K US dollars. To find the same home in the US at 3x the price would not only be almost impossible, but would most definitly require additional large funds to be habitated. That aside, this statement by the journalist, Aarti Dhar, is also false: surrogacy is most certainly allowed throughout the US. A few states may have particular laws disallowing it, but all one has to do is find a surrogate in a different state if there is any concern.

The statement on Europe is equally false as there is more than one European country that allows surrogacy, though like India, some do not have specific regulations in place. Even for the majority that do disallow it, the US has long been a place (much longer than India) for Europeans interested in surrogacy. Legal problems that were encountered in the US initially, such as the 1986 Baby M case, have been resolved by using gestational surrogacy only versus the traditional surrogacy.


The core principles of journalism dictate truthfulness, accuracy, objectivity, impartiality, fairness and public accountability. Since this article is not listed under the Opinion section and instead falls under the National section, it fails on all accounts. We can not address how women are being exploited in these circumstances, and I believe there is a high liklihood that they are in many places, if our newspapers do not give the information accurately and without bias. More importantly, we can not attempt to fix it. Very disappointing that The Hindu, with such a illustrious history and excellent reputation, failed on such a basic level.

Thursday, June 14, 2012

Front page, bottom fold


Picture from article

Reading "The Times of India" (inclusive of "Ahmedabad Times" version) I was immediately struck by the article on the front page, bottom fold: Womb rental incubated her business - Surrogate Mother Invest Earnings.


--by: Bharat Yagnik


Ahmedabad: Madhu Solanki is a 34-year-old successful businesswoman running one of the largest grocery stores in her village, Waghpur near Anand. Madhu got the seed investment for her business from her womb, literally!

In 2006, Madhu had given her womb on rent. She had opted to become a surrogate mother for a childless couple from Bangalore to get out financial crisis - she along with her husband struggled to run the family on a meager income of Rs 4,000 per month. She got 2.25 lakh for renting out her womb. Madhu could save Rs 80,000 after building a small house.

Instead of depositing the money in a bank, Madhu decided to start a business. "There are three-odd grocery stores in my village. Being a woman I knew precisely what ingredients women need for their daily routine. The learning curve was difficult but I got the hang of the business in a few years," says Madhu, who owns the Anand Grocery Store. The store's daily collections now stand at Rs 10,000. Given her huge success, she has been appointed as a trainer to make entrepreneurs out of eight other surrogates who have earned decent money and are keen to invest it wisely so that they become financially independent.

"Madhu has trained eight surrogates who are in the throes of beginning their own grocery business. We want more women to stand on their feet," said surrogacy specialist Dr Naina Patel.

Madhu is a mother of two sons - one 10 years old and the second was born after she bore a child through surrogacy. Madhu and her husband are keen to give good education to their sons. "Becoming a surrogate changed my life. But the key is not to spend the money but use it to become financially independent for life," says Madhu.