Showing posts with label Akanksha. Show all posts
Showing posts with label Akanksha. Show all posts

Sunday, October 7, 2012

New Advances in Infertility

Each of these mouse pups was born from an egg scientists created using embryonic stem cells. 
On thursday, NPR had a fascinating story on a breakthrough discovery for infertility. Even more fascinating  they did it with induced pluripotent stem cells (as opposed to the controversial embryonic stem cells). If they can do it for women, then not only will it reduce/eliminate the biological clock worry, but also provide a solution for the dreaded "unexplained infertility" diagnosis that plagues so many women. This will be a game changer for future generations of infertile women. There are even great implications for men with sperm issues, as well  as the many hurdles faced by the LGBT community.

Alas, this will not apply to many of us currently in the throes of infertility. All is not lost. Many doctors are currently working on various cell technologies that apply to infertility. Autologous Endometrial Coculture is one example of a technology promising encouraging results. What does all that fancy wording mean? The short of is that they take cells from the lining of a woman's uterus and use them as a more natural environment for fertilized eggs than the previous methods. Studies have shown that in certain cases embryo development is improved, as are IVF success rates.

Dr. Patel's clinic in India is working with a similar concept: certain clients can qualify for the case study in which natural cells from the IVF patient are used to surround the egg pre-fertilization. They are seeing an increase in fertilized eggs and while it's too early to determine if this results in actual healthy babies born, I can say I was very impressed to learn that 3 out of 4 of my eggs were fertilized with this method. There is more to this method than I am [purposely] describing, but that is better left to the professionals or perhaps, when I can be less emotionally attached to the subject matter.

I have no idea if this will help the quality of my eggs/embryos in the long run, but it is still very exciting. My first cycle ended up with 2 eggs and only 1 of those fertilized. That 1 egg took over 24 hours to fertilize. On my second cycle (with the new protocol) I had 4 eggs extracted and out of those 3 fertilized. Like my first cycle, one of those was a late bloomer, but maybe it's the one implanted now and thus causing a lower hcg. Apparently my case is not an anomaly as the Akanksha Infertility Clinic is seeing really encouraging results with women that qualify for the case study. Even if it doesn't work for me, I will be really excited if this helps improve success rates for women in general.

Science is so cool. 

Tuesday, September 25, 2012

Bye bye India

Sniff sniff.

I met some really great people this trip: some only briefly and some were there every step of the way. (And to the cute girl asking me if she should blog - YES! I won't mention your name in case you want to end up going incognito like me, but I think it would be great if you did.) Best of luck to all my fellow IVFers and surro buddies.

Would also like to mention how much I really like our surrogate. She is a beautiful (inside and out), healthy, bright, and charming young woman. Exactly what I hoped for. Hopefully, fate will shine down on us in this and in the future.

Was happy to have a chance to see some of our family while we were here, even if only briefly. Wish we had more time, but alas it was not so.

So much to write, but I'm on my phone and need to start prepping for our long flight, so I'll cut it short for now. Made lots of notes along the way, to write for a different day.

Bye bye India. Hope to see you soon.

Thursday, September 20, 2012

Egg total = 4

Less than I thought for 12 good follicles, but still twice as many as last time.

Today we go and see if they fertilized. Already my stomach is a tad in knots. 

Tuesday, September 18, 2012

Day 9: 12 are good to go!

12 follicles are between 16-21mm and 1 is at 14mm. YAY YAY YAY. This is so much better than last time (and with the original 5 we thought we were starting with). I'm still on the antagonist protocol, but with extra meds that Dr. P says has recently shown really good results in poor responders. Now let's just hope everything else goes well and that the follicles are filled with good eggs, that make good embryos, that make BABIES. It would really suck to feel so positive this time to have it all go to crap.

We are going to retrieve on Thursday. My husband has switched his travel plans and it taking an earlier flight into Vadodora, where the hotel car will be waiting for him. We nixed the train idea. That should shave a few hours off his time, so maybe he will make it before I go under. I hope so.

My husband wanted me to ask the doctor if we could do the retrieval in the afternoon, but she said she doesn't want to take the chance and compromise everything. I knew that would be the case. If we don't time things exactly right, then we could miss our window, especially with my larger follicles.

So Thursday it is. Right now my husband should arrive around 8:30AM and I am scheduled for retrieval at 9:30am. With any luck he will be there to hold my hand before I have to go under. Hoping that Dr. P is able to retrieve many and that they are good.

While we are waiting, here are some pics of a small local temple nearby.





Monday, September 17, 2012

Day 8: Yay! and try not to freak out.

Had another sonogram today, more shots, met the surrogate, and went over some preliminary paperwork.

Sonogram showed 13 follicles (yay!). 5 really good size, 6 average, and 2 small. Hopefully we will get some good eggs and then embryos out of these. Right now we plan on extracting on Thursday, but Dr. P said she will confirm after my sonogram tomorrow. 

Starting to get a little worried with the timing of my husband's arrival. I recall when we were planning this trip that I commented we didn't have much buffer room for mess-up (time wise), but I didn't think much more of it. Don't think I even thought of the timing for HIS arrival at all. Saturday I realized how short we were cutting it with his arrival. He gets here on Thursday - right now I'm tentatively scheduled for egg retrieval that day. That means he will not be there when I go under, something I am NOT happy about. Think "scared" is more the word I am feeling around for. In case of emergency, we do have 2 backup samples from last time, which is  good to know, but still don't like the idea of possibly having to use them if ANYTHING goes wrong with his travel. 

Try not to freak out, Try not to freak out. 

Last time we had to go a day earlier than expected. We expected 10 days of shots (not including the trigger) and ended up with only 9. If I go on Thursday, this will mean that I only had 8 days. I think the average person goes 9-12 days. I'm hormonal and irritable at my husband right now. Even more at myself for not looking at his schedule more closely and insisting on better buffers. 

Try not to freak out. Try not to freak out. 

Ok, got that out of my system for now.

On a different note: met the surrogate today. The surrogate is 28 years old, 121 lbs and 5'3 (I think she's 5'2 1/2). She has a brightness to her eyes and is ready with a smile. Sadly, she is going through a divorce and wishes to have enough money to get her own house and have some left over to go towards her son's education. 

When people talk about exploiting the poor, I really wonder if they think of things like this. Many months ago I looked up Gujarat house/flat prices and I remember being amazed how low they were. A surrogate in the USA could NEVER buy a house for what a woman could here in India. Sure, it may be a small house/flat compared to what we are used to, but so are most of the homes I have been to here. Even in very well to do homes. A woman could not earn the equivalent of 10+ years salary for surrogacy in the USA and they could not have left over funds to educate their children. When you see the lives here that have had such a positive impact due to Dr. Patel and surrogacy, it's easy to see why she does not let her critics affect her. 

Ok, got that out of my system for now.

Please let this take this time. I don't think we could come back again for another try with my eggs. Please please please. 

Hopefully this cow gave me her blessings. I gave her and a baby cow some of my leftover Malai Kofta and rice. Actually I gave it to the calf, but then she came and took it over. I'm ok with that. Maybe I'll get double blessings. 

Boss cow

Baby cow eating bushes after a few bites of delivery

Sunday, September 16, 2012

Good article about surrogacy in India

Not familiar with this news source here in India, but the few articles I perused were done quite well. The article they have on surrogacy is here: http://gulfnews.com/life-style/general/india-s-rent-a-womb-industry-is-booming-1.1073056. Though I don't particularly care for the first picture they have in the slides, the article is a positive one none-the-less. Worth the read.

Note: the article is a bit confusing when it is referring to clinics . Even as a person who knows a ton about my clinic, I had some confusion when they flip between some details about clinics. For example, on page  1, the author writes "Parvati works for – Akanksha Infertility Clinic" and noting earlier that is is located in Ahmedabad. Then they flip to "Dr Kamini Patel, the director of Vani IVF Centre, in Ahmedabad". Even though these two clinic are in Gujarat and both have a Dr. Patel, they are two completely different clinics. The article flips back and forth between quotes from Parvati and quotes from Dr. Kamini, that it sounds like they are the same clinic. I actually wonder if they just misprinted which clinic Parvati was with. 

Also, while the Vani IVF Center they refer to frequently and write as having 48 surrogate babies born, I do want to note that Dr. Nayna Patel at the Akanksha Infertility Clinic has had over 500 surrogates born as of June of this year. I know this because I was here for the HUGE celebration, flanked with media from all over. I include this information because I can see that the most people would confuse the two clinics when reading the article

Saturday, September 15, 2012

Days are flying by: Day 6 - Part deux

Good and bad.

The bad was the AMH results, but for reasons I will not go into right now, I don't have absolute confidence in the results from the blood peeps. That could be a preserving mechanism, could be erroneous results, maybe my cyst threw it off, or maybe the results were simply wrong. Whatever. I'm not going to focus on that either way. PLUS, from what I understand, AMH is a direct reflection of follicle/egg count and if that's the case then it doesn't make sense that....


MY FOLLICLES ARE WAY UP! I have 11 that are growing. 7 of them are good sized. The 4 smaller ones can always potentially catch up, but I'm very happy about the 7 follicles. That's much better than last time.

(pic my send friend sent me during my 1st cycle)


I realize that 11 follicles isn't earth shattering news for some, but it's great news for me. Let's just hope that they have good eggs inside and that will grow into great embryos. 

Tuesday, September 11, 2012

Day 1 and 2 with the doc

Some of my meds

Yesterday was my first visit with the doctor. We thought we were going to have to aspirate my cyst, but Dr. P thought we should check my hormone levels first. We would only aspirate if the hormones were off.

 Last cycle I had a 3cm cyst and my estradiol was way off. I only had 3 follicles and we had to aspirate in order to proceed and get my hormones back in line. Once it was aspirated (general anesthesia - ACK!), we saw 14 follicles. Not exactly sure how that works (were they hiding???, why were we able to see more later on the unaffected ovary?), but that made the initial panic of 3 follicles easier to deal with.

This time I knew I had a 5cm cyst walking in. Turns out it had reduced to 2cm, but I only have 5 follicles currently showing. 4 and 1. My hormone levels came back normal, so we opted not to aspirate. Dr. P ordered an AMH test, and I get the results back tomorrow. Truthfully, I am a bit horrified to get the results back from that one. The follicle thing I can not worry about and simply hope more "appear", but a bad AMH right off that bat will crush me.

We are starting off with a stronger course of meds this time, though the Gonal F is at the same range we started last time (we increased it halfway through last time). 4 shots to the belly right now. Here is the breakdown:

gonal f - 375 IU
luveris/lutropin - 75 x .2
lupride/ leuprolide - 1. mil IU
human chorionic gonadotropin (hCG): HOCOG - 1250 IU

I started researching some stuff yesterday and then I just stopped. It was too depressing and I don't think it is doing me any favors right now. Hopefully my AMH has not tanked (it was 1.7 in February) and then I can be cautiously hopeful. Not even sure if cysts can affect AMH, but I'm too afraid to keep looking. 

Today I'm ok. Got shots in the belly and then socialized a bit with some other patients. For some reason, buying dog food to leave for homeless dogs (I especially worry about the lame ones) made me feel better. I don't know why, it just did. Maybe because it gives me a little bit of control or maybe it's because I feel like I can do a little tiny something to help. Right now I need a super simple way to make myself happy and that did it. I'm sure there are plenty of more laudable things I could be doing right now, but that comes with such complications at times and often tons more stress. 

I'll confess that in the last few weeks, I have, on occasion, semi-prayed. Given my atheist/agnostic ideology, this is quite complex to me internally. Not posting this because I want I bunch of comments regarding religion (quite the opposite), I just thought since it is part of my journey that I better fess up. If you are religious and are reading this, feel free to send your prayers, good vibes, or whatever else my way. I need all the help I can get. :-)

That's it for now. 

Sunday, July 22, 2012

Open letter to The Hindu (newspaper)

Thanks to Douglas over at Just One Out of Seven Billion for bringing an article by The Hindu, to my attention.  Below is an open letter to the editor based on a similarly emailed letter.

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Regarding your article here: http://www.thehindu.com/news/national/article3640405.ece, I am surprised and saddened to see such a bias-based article written by The Hindu. There are several misrepresentations that I will list for your consideration.


1.) Thanks to the emergence of surrogate motherhood as a multimillion-dollar industry in the country, the clinic is doing a roaring business. What is the success formula? An unending supply of poor and illiterate women and the absence of laws have made the trade the fastest way to make money.

No source referenced here (a mainstay of good journalism) on how the author came to the conclusion that this specific clinic's success is based on [the uteri] of poor/illiterate women. No mention on how the clinic in question has put a lot into the community to educate the surrogates and their children. No mention of the trust fund set up to assist current and previous surrogates to further themselves and their family. A simple query into the community will show you that Dr. Patel is highly revered for all she has done to help the women in her care. Simple research into print editions of The Times of India (Ahmedabad edition) or Hindustan Times would have shown this as well. Had the author inquired into proof of how the surrogates have had their lives changed by this clinic, then Dr. Patel would have been able to provide this.


2.) Another inmate had four foetuses in her womb, two of which were aborted as the couple did not want so many children. There is no clarity on whether two foetuses were aborted for medical reasons. 

Using the emotional term "inmate" aside,  a woman carrying 4 foetuses to full term is in extreme danger, as are the foestuses. A rudimentary check with a few respectible obstetricians would have enlightened this fact. A woman's survival rate and the babies survival rate is seriously compromised and often considered not worth the risk. A doctor that WOULD allow this should draw much more concern as in cases where it is allowed, it would appear that the woman's health is not the priority.


3.) A commissioning couple can get a surrogate for half the price in India compared to the cost in the U.S. or the U.K., where surrogacy is not allowed or permitted only in special cases. European countries do not allow surrogacy at all. 

While I could lament on the economic differences between these countries and how comaparing them is extremely misleading, I will simply point out the cost of the average 1000 sqft flat in Vastrapura (located in the state of the clinic mentioned in this article) to allude my point: the [current] equivelent of 12-16K US dollars. To find the same home in the US at 3x the price would not only be almost impossible, but would most definitly require additional large funds to be habitated. That aside, this statement by the journalist, Aarti Dhar, is also false: surrogacy is most certainly allowed throughout the US. A few states may have particular laws disallowing it, but all one has to do is find a surrogate in a different state if there is any concern.

The statement on Europe is equally false as there is more than one European country that allows surrogacy, though like India, some do not have specific regulations in place. Even for the majority that do disallow it, the US has long been a place (much longer than India) for Europeans interested in surrogacy. Legal problems that were encountered in the US initially, such as the 1986 Baby M case, have been resolved by using gestational surrogacy only versus the traditional surrogacy.


The core principles of journalism dictate truthfulness, accuracy, objectivity, impartiality, fairness and public accountability. Since this article is not listed under the Opinion section and instead falls under the National section, it fails on all accounts. We can not address how women are being exploited in these circumstances, and I believe there is a high liklihood that they are in many places, if our newspapers do not give the information accurately and without bias. More importantly, we can not attempt to fix it. Very disappointing that The Hindu, with such a illustrious history and excellent reputation, failed on such a basic level.

Friday, June 15, 2012

Happy Birthday to baby 500 and 501!!!

Sign at Dr. Patel's clinic
Today was very exciting at the clinic and we were asked to stay after our shots. They were having a major celebration as the 500th surrogate baby was born today (technically it was twins, but the focus was on #500). We were more than happy to stay for the festivities.

After popping 2 balloons to help decorate, I gave up. One of the doctors teased me that it was a good thing no one was near delivery time because of the loud bangs. Had not realized so much media would be there and it was a little overwhelming for me as those things tend to be. I was pulled over for some photos, but I'm fairly certain that I didn't even make the crop. I seemed more in the way then anything else.

There were babies all around, but the
two new stars were the focus. There were so cute, and despite their tiny size, looked healthy. Dr. Patel worked her magic with the media and as always, was stunning to watch.

After all the interviews, cake and samosas were passed around. Yum! I needed some sugar after all of that excitement. A gorgeous 5 year old girl had taken a shinning to me and I thought of her as we exited the clinic.

Tuesday, June 12, 2012

First day jitters

Our nice A/C waiting room is for IVF peeps only. We waited only a short time (by universal doctor standards) to have our initial consult and then blood drawn. After which, we grabbed some lunch at The Rama Hotel's Thalis restaurant. Both my husband and myself enjoyed it very much, although it was on the sweeter side of his preference - typical of Gujarati cuisine according to him.

After lunch, we came back to the clinic as directed. After another short wait we were able to see Dr. Patel. She was concerned about a high estradiol level and we went over the dreaded "you're 40 speech". I appreciate the honesty, but that is one "tut-tut" I've grown weary of, regardless the source. We followed up with a scan that gave us more bad news: only 3 follicles and a 2cm cyst. The cyst would have to be aspirated to insure the highest chance of success. Come back at 5:30pm. Eat or drink nothing.

"Ok!!!! Wait what?" We had 3 hours to burn in the heat of Anand (currently at 104 F) and I was instructed not to drink. Fine. We took a rickshaw/tuk-tuk (my first ever!) to the famed Big Bazaar (BB) where even the girls in Bedazzled burkas stared at me. The BB here is like a really tiny Walmart with food items. Even though the drinks were in a refrigerated area, the want to drink was too much and I walked back over to the skin lotion aisle. The Nivea whitening lotion I bought is a testiment on how well marketing works (I've seen the commercial 30+ times now, and it has convinced I'm covered in spots from skin damage, even though I'm not positive that's what the Hindi spoken commercial says.)

After BB, we return to the hotel for an hour, and then back to the clinic. At the clinic, in a not so A/C area, I'm handed a consent form to sign. I ask what it is for and I understand it is for the anesthesia; it's at this point I realize I will be getting GENERAL anesthesia and not local. Ask my husband to confirm this and he does. Crap. I'm not known for doing well under general anesthesia. I prepare myself (and others) for the liklihood of puking.

Fortunately, I did not puke when they woke me up, but my husband was asking me what the class of antibiotics was that I have a problem with. Once we figured that all out, an older lady in a white sari added a yellow liquid filled syringe to my empty IV. They let me rest till I was good and ready to come back downstairs.

Dr. Patel informed us that once the cyst was aspirated, she could see 14 follicles. Yay!!! I had to confer with my husband that I understood correctly. Not because any language barrier, but because I still felt a little loopy. He said yes and I was jubilant, if not completely dexterous.

That pretty much was the end of our first day. We went back to the hotel for me to rest, which really turned into me going to bed for the night. My poor husband missed dinner for the second night in a row.

Off to see the wizard


In the waiting room
One can safely say the traveling to a different country, even one you have been to before, is a bit like Oz. Sometimes it's stormy and things are quite different. India is no exception. It's been a few days, but I think it will be a few more before I'm not dizzy from the tornado anymore.

This morning I was able to awake early, mostly because I played catchup with sleep yesterday and last night. I woke around 5am and my husband woke just around 6am. Even so, we relaxed as we got ready - until the luke warm shower startled me awake.

Our room at La Casa is very nice and even though it's a little farther from the clinic and though most westerners are at the closer Rama, I am glad we chose it. My husband thinks they may have upgraded us.

The tiny rocks in my sandals are an attest to us getting a little lost, but now we are sitting in our air conditioned room (separate from the regular clients) with 4 other ppl: an Indian couple and an Indian woman with her mother. I'm fairly certain this is the IVF room and tell my husband as much. I overhear the word "cycle" mixed with Hindi and I feel confident in my guess.

Now we wait. There is an autographed picture of Oprah watching over us (Dr. Patel was on her show) next to the god Ganesh. Between the two, I'm hoping at least one will shine favor upon us.

Tuesday, April 3, 2012

Just the quote I needed today

Just started my new book, The Sacred Thread: A True Story of Becoming a Mother and Finding a Family - Half a World Away, and the opening page has this quote:

"At one end of this world, there is one woman who desperately needs a baby and cannot have her own child". And at the other end, these is a woman who badly wants to help her own family. If these two women want to help each other, why not allow that? They're helping one another to have a new life in this world."


   --Dr. Nayna Patel, medical director
      Akanksha Infertility Clinic
      Anand, India

Exactly.